NMJ Development and Degeneration

The Nishimune Lab focuses on defining molecular, cellular and circuit-level mechanisms that govern neuromuscular junction formation, maturation and maintenance, with an emphasis on how synaptic defects contribute to neuromuscular disease and motor dysfunction.

PI Bio

Lab Focus

Research Interests:
1. Investigations of degeneration mechanism and development of interventions for aging of the neuromuscular system
2. Investigations of degeneration mechanism and development of interventions for amyotrophic lateral sclerosis
3. Molecular and structural analysis of synapses

Areas of Expertise:
1. Nervous system and neuromuscular junction research
2. Development, aging, and disease of the neuromuscular junction
3. Anatomical and molecular study of the synapse
4. Super-resolution STED microscopy