Dysmyelinating Neuropathy Mechanisms

The Moss Lab focuses on uncovering molecular, cellular and systems mechanisms regulating myelin biology and peripheral nerve dysfunction, with a particular emphasis on Charcot-Marie-Tooth disease (CMT) and related inherited neuropathies.

Moss Lab

Research Interests:

1. Fundamental mechanisms of peripheral nerve myelin biology and myelin domain architecture in health and inherited peripheral neuropathy
2. Multiscale mechanisms underlying disability and functional impairment in inherited peripheral neuropathy
3. Development of novel modeling systems and therapies for inherited peripheral neuropathy

Areas of Expertise:
1. Peripheral nerve biology, myelin architecture and axoglial domain organization
2. Mouse models of neuromuscular disease and high-resolution nerve imaging
3. Translational neuromuscular research integrating molecular, structural and functional approaches