Weakness and Fatigue in Aging and Disease
The Kelly Lab investigates the mechanisms underlying motor dysfunction and fatigue in aging and neuromuscular disease. By integrating advanced neurophysiological techniques with clinically grounded rehabilitation research, the lab aims to develop evidence-based, patient-centered interventions that preserve mobility, enhance motor performance and maximize healthspan across adulthood.
Lab Focus
Research Interests:
1. Physiological mechanisms underlying weakness and fatigue in aging and neuromuscular disease
2. Peripheral and central regulation of motor unit function across health and disease
3. Exercise and rehabilitation strategies to preserve motor performance and mobility
4. Mechanistic overlap and divergence between healthy aging and neuromuscular disorders
5. Development of patient-centered interventions to improve function and quality of life
Areas of Expertise:
1. Neuromuscular rehabilitation and neurologic physical therapy
2. Motor unit physiology and neurophysiological assessment
3. Transcranial magnetic stimulation and advanced electromyography techniques
4. Clinical and translational research in aging and neuromuscular disease
5. Exercise-based and behavioral interventions for functional preservation