Proprioception and Peripheral Nerve Aging
The Castoro Lab investigates mechanisms underlying proprioceptive dysfunction and peripheral nerve aging across the lifespan. By integrating clinical neuromuscular research with molecular, structural and physiological approaches, the lab aims to define how aging alters sensory and motor nerve function and to identify strategies that preserve mobility, balance and neuromuscular health.
Lab Focus
Research Interests:
1. Mechanisms of proprioceptive decline during aging and neuromuscular disease
2. Peripheral nerve aging and age-related sensory dysfunction
3. Interactions between sensory feedback, motor control and mobility impairment
4. Translational studies of neuromuscular aging and functional decline
5. Therapeutic strategies to preserve peripheral nerve function and resilience across the lifespan
Areas of Expertise:
1. Peripheral nerve physiology and sensory neuron function
2. Proprioception, balance and neuromuscular performance
3. Clinical and translational studies of neuromuscular aging
4. Functional assessment of sensory and motor impairment
5. Integration of mechanistic neuroscience with patient-centered neuromuscular research